Calu-3 is a tumorigenic cell line that was established from the lung tissue a 25-year-old Caucasian male with adenocarcinoma. The patient had been treated with Cytoxan, Bleomycin, and Adriamycin before the tissue sample was taken. Calu-3 has a hypotriploid stemline chromosome number and expresses antigens blood type A and Rh+. Calu-3 cells display an epithelial morphology and adherent cultural properties. The Calu-3 cell line can be used to study lung cancer by following in vivo or in vitro transfection methods, and Altogen Biosystems has a Calu-3 xenograft model and a Calu-3 Transfection Reagent commercially available.
The Calu-3 cell line was derived from the carcinomatous lung tissue of a 25 year old Caucasian male suffering from adenocarcinoma. Before the cell line was established the patient had received therapy with bleomycin , cytoxan, and adriamycin. The tumorigenic, epithelial cells of the Calu-3 cell line are now used to produce a transfection host model for various types of lung cancer as well as other biomedical research. The Calu-3 transfection reagents established by Altogen Biosystems allow an intracellular delivery of pDNA, mRNA and siRNA and the recombinant protein expression desired in certain research. Calu-3 Transfection Reagent (Lung Carcinoma Cells, HTB-55)
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